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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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Norepinephrine (Levarterenol; L-Noradrenaline) tartrate is a potent adrenergic receptor (AR) agonist that activates α1, α2, and β1 receptors. It is generally considered a β1-subtype selective adrenergic agonist over β2-adrenoceptor, but also has direct activity at the β2-adrenoceptor in higher concentrations.
Potent adrenergic receptor (AR) agonist
β1-subtype selective
For research purposes only
High purity: 99.96%
Used in various research areas
Can be used to induce cardiomyopathy in animal models
Involved in multiple clinical trials for various conditions
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Aminooxy-PEG3-azide is a PEG-based bifunctional linker containing an aminooxy (hydroxylamine) group and an azide group for orthogonal bioconjugation. It enables oxime formation with aldehydes or ketones and azide-alkyne click chemistry, and is supplied as a liquid at high purity for lab-scale synthesis.
Contains aminooxy and azide functional groups for orthogonal conjugation
Enables oxime ligation and azide-alkyne click reactions
Suitable for ADC, PROTAC, and general bioconjugation workflows
Supplied as a liquid with high laboratory-grade purity
Available in small-scale pack sizes for research use
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NHPI-PEG3-C2-Pfp ester is a noncleavable, trifunctional 3-unit polyethylene glycol (PEG) linker bearing an N-hydroxyphthalimide (NHPI) group and a perfluorophenyl (Pfp) activated ester. It is used for bioconjugation and in the synthesis of antibody-drug conjugates (ADCs). Intended for research use only.
Noncleavable 3-unit PEG linker
NHPI functional group for site-specific conjugation
Perfluorophenyl activated ester for amine coupling
Molecular weight about 533.4 g/mol; formula C23H20F5NO8
Purity greater than 96%
Intended for research use only, not for human or animal use
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(S)-2-(2-((tert-Butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid (Boc-his(trt)-aib-ohol) is a drug intermediate for synthesis of various active compounds
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Mal-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
PEG-based PROTAC linker
Used in PROTAC synthesis
Exploits the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
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NH-bis(PEG3-azide) is a PEG-based PROTAC linker used in PROTAC synthesis. It is a click chemistry reagent containing an Azide group, which can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne groups or strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
Can be used in the synthesis of PROTACs.
Contains an azide group, facilitating click chemistry reactions.
Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups.
Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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